To articulate and undertake a transformative approach to the development of responsible, culturally appropriate, nationally consistent and internationally relevant Indigenous genomics efforts.
Establish: Establish an Indigenous Genomics Network that provides leadership, coordination and alignment of expertise, and maximises benefit.
Enhance: Enhance Indigenous community understanding of, involvement in, and leadership of genomics research and health care.
Identify, develop, and communicate: Identify, develop, and communicate critical genomic policies of direct relevance to Indigenous Australians, health care providers, and policy operatives.
Define, share and support: Define, share and support the implementation of nationally consistent, culturally appropriate ethical, best-practice, genomic data and sample storage, management and sharing.
Build: Build the capability of an Indigenous Genomics clinical and research workforce.
Define, plan and implement: Collaboratively define, plan and implement clearly articulated pathways to benefit for Indigenous Australians as a direct result of genomics research and health care.
Each node will coordinate efforts to inform core ALIGN activities in 1) Indigenous Governance of genomics research and clinical care; 2) the development of best practice data systems and data sovereignty; 3) genomics policy; and 4) developing capacity.
These represent key foundations to ensuring the equitable receipt of benefit from genomics.
In addition, each node will coordinate a Flagship Program that lays the foundations and articulates clear plans for what is required to deliver meaningful benefit to Indigenous communities. These flagships will initially focus on a) Pharmacogenomics; b) Precision Medicine; c) Immunogenomics; d) Genome Variation; and e) Rare Diseases.